Hyaluronic acid (HA)
exists naturally in all living organisms. In the body,
it is found in greater concentrations in the synovial
fluid of joints for lubrication, the vitreous humor
(fluid) of the eye and most abundantly in the skin.
As we age, the body
produces less and less hyaluronic acid. This has an
effect on normal, smooth, comfortable joint movement
and normal softness and smoothness of the skin. You
can maintain normal mobility, proper skin condition,
the skin's self-smoothing ability, and clear healthy
eyes with Synthovial Seven.
Synthovial Seven®
is an oral solution made from premium grade hyaluronic
acid with high molecular weight. Hyaluronic acid is a
polymer and it can come in varying molecular weights.
Studies have shown more benefits with the higher
molecular weight HA polymers.
Synthovial Seven®
is a liquid solution of hyaluronic acid. Oral
solutions by nature are absorbed by the body easier
and quicker than tablets and capsules.
Hyaluronic Acid: History, Chemical Structure, and its
Benefits for the Body
What is Hyaluronic Acid?
Hyaluronic Acid(HA), also known as
hyaluronan or hyaluronate, is a carbohydrate, more
specifically a mucopolysaccharide occurring naturally
throughout the human body. It can be several thousands
of sugars (carbohydrates) long. When not bound to
other molecules, it binds to water giving it a stiff
viscous quality similar to “Jello”. This viscous Gel
is one of the most heavily researched substances in
medicine today with thousands of trials mostly in the
fields of orthopedics and eye surgery. Its function in
the body is, amongst other things, to bind water and
to lubricate movable parts of the body, such as joints
and muscles. Its consistency and tissue-friendliness
allows it to be beneficial in skin-care products as an
excellent moisturizer. Because HA is one of the most
hydrophilic (water-loving) molecules in nature with
numerous benefits for the human body it can be
described as "nature's moisturizer".
Hyaluronic Acid
Benefits for the Body?
If we compare the
joints of the human body to an automobile engine, the
joint fluid in the body mimics the oil in a car engine.
At regular intervals we replace the oil in our car
engines because the heat and friction breakdowns the
oils viscosity. The oil becomes thinner and less able to
protect the metal surfaces from excessive wear.
Hyaluronic acid benefits our joints in the same way. As
we age the viscosity of the joint fluid lessens. HA
helps to maintain normal joint cushioning.
What is Hyaluronic
Acid's Chemical Structure?
It is naturally
produced in the human body and is chemically classified
as a Glycosaminoglycan. In the body, hyaluronic acid
always presents itself as a large high molecular weight
molecule. The molecule is made up of a repetitive
sequence of two modified simple sugars, one called
glucuronic acid and the other N acetyl glucosamine.
These compounds are both negatively charged and when put
together, they repel producing an exceptionally long
stretched out molecule (high
molecular weight). HA molecules that are long and
large in size produce a high viscosity (lubrication)
effect which resists compression and allows our joints
and skin to bear weight.
When was Hyaluronic
Acid discovered?
HA was first used
commercially in 1942 when Endre Balazs applied for a
patent to use it as a substitute for egg white in bakery
products. Its discovery was very unique. No other
molecule had ever been discovered that has such unique
properties to the human body. Balazs went on to become
the leading expert on HA, and made the majority of
discoveries concerning hyaluronic acid benefits.
Where is Hyaluronic
Acid located in the body?
Hyaluronic Acid is
found naturally in most every cell in the body and
occurs in high concentrations in specific body
locations. In each body location, it serves a different
function. Unfortunately, HA also has a half-life ( the
time it takes for the molecule to get broken down and
excreted from the body) of less than 3 days and possibly
even as little as one day in the skin. For this reason,
it is imperative that the body continually replenish
itself with HA. Below are some of the areas in the human
body where it is present and critical to anatomical
function.
Hyaluronic Acid in
Bones and Cartilage
Hyaluronic Acid is
found in all bones and cartilage structures throughout
the body. 
Both of
these structures provide a resilient rigidity to the
structure of the human body. HA is especially found in
various forms of cartilage but none more than the
hyaline cartilage. As you've probably guessed it,
hyaline is short for hyaluronic acid. Hyaline cartilage
covers the ends of the long bones where articulation
(bending) occurs and provides a cushioning effect for
the bones. The hyaline cartilage has been called the
"gristle cartilage" because its resistance to wear and
tear. Hyaline cartilage also supports the tip of the
nose, connects the ribs to the sternum and forms most of
the larynx and supporting cartilage of the trachea and
bronchial tubes in the lungs.
Hyaluronic Acid in
Synovial fluid
Our joints (like the
elbows and knees) are surrounded by a membrane called
the synovial membrane which forms a capsule around the
ends of the two articulating bones. This membrane
secretes a liquid called the synovial fluid. Synovial
fluid is a viscous fluid with the consistency of motor
oil. It has many functions, but none more than providing
the elastic shock absorbing properties of the joint. Its
second most important function in the joint is to carry
nutrients to the cartilage and to also remove waste from
the joint capsule.
Hyaluronic Acid in
Tendons and Ligaments/Connective tissue
Connective tissue is
found everywhere in the body. It does much more than
connect body parts; it has many forms and functions. Its
major functions include binding, support, protection,
and insulation. One such example of connective tissue is
the cordlike structures that connect muscle to bone
(tendons) and bone to bone (ligaments). In all
connective tissue there are three structural elements.
They are ground substance (hyaluronic acid), stretchy
fibers (collagen and elastin) and a fundamental cell
type. Whereas all other primary tissues in the body are
composed mainly of living cells, connective tissues are
composed largely of a nonliving ground substance, the
hyaluronic acid, which separates and cushions the living
cells of the connective tissue. The separation and
cushioning allow the tissue to bear weight, withstand
great tension and endure abuse that no other body tissue
could. All of this is made possible because of the
presence of the HA and its ability to form the
gelatinous ground substance fluid.
Hyaluronic Acid in
Scalp Tissue and Hair Follicles
Structurally the scalp
is identical to the skin tissue located throughout the
body except it also contains about 100,000 hair
follicles that give rise to hair. Actually the hair and
the hair follicle are a derivative of skin tissue. There
are two distinctive skin layers, one, the epidermis
(outer layer) which gives rise to the protective shield
of the body and the other, the dermal layer (deep layer)
which makes up the bulk of the skin and is where the
hair follicle is located. This dermal layer is composed
of connective tissue and the connective tissue, with its
gelatinous fluid like characteristics provides support,
nourishes and hydrates the deep layers of the scalp. The
result is healthy lustrous hair and a moisturized scalp.
Again, all of this is made possible because of the
presence of HA in the scalp.
Hyaluronic Acid in Lips
The lips are a core of
skeletal muscle covered by skin tissue. The dermal layer
of the lips is composed primarily of connective tissue
and its components hyaluronic acid and collagen that
give the structure (shape) and plumpness to the lips.
The HA binds to water creating a gelatinous fluid that
hydrates the surrounding tissue and keeps the collagen
(responsible for keeping the skin tight) nourished and
healthy. The result is healthy well hydrated and plump
lips that are well protected from the environment.
Hyaluronic
Acid in Eyes
Hyaluronic acid is
highly concentrated inside the eyeball. The fluid inside
the eye called the vitreous humor is composed almost
completely of hyaluronic acid. The HA gives the fluid
inside the eye a viscous gel like property. This gel
acts as a shock absorber for the eye and also serves to
transport nutrients into the eye. HA has been directly
injected into the eye during procedures to help maintain
the shape of the eye during surgery. It has been said
that after the 5th decade of life, our eyes stop
producing the much needed hyaluronic acid resulting in
various eye needs.
Hyaluronic Acid in Gum Tissue
The Gums (gingivoe)
are composed of dense fibrous connective tissue
(ligaments) which secure the teeth to the aveloar bone
(jaw bone). Once again, connective tissue is composed of
a fibrous tissue surrounded by hyaluronic acid
(extra-cellular matrix). Without the presence of HA, the
gum tissue becomes unhealthy. If it is present it helps
to provide the tensile strength of the ligaments that
secure the tooth in place by providing hydration and
nourishment. The result is a healthy set of gums.
Skin
Although Hyaluronic
Acid (HA) can be found naturally in most every cell in
the body, it is found in the greatest concentrations in
the skin tissue. Almost 50% of the bodies HA is found
here. It is found in both the deep underlying dermal
areas as well as the visible epidermal top layers. Young
skin is smooth and elastic and contains large amounts of
HA that helps keep the skin stay young and healthy. The
HA provides continuous moisture to the skin by binding
up to 1000 times its weight in water. With age, the
ability of the skin to produce HA decreases.
ECM (ground
substance)
The extracellular
matrix (ECM) is a gelatinous (gel-like) fluid that
surrounds almost all living cells and is essential to
life. It gives structure and support to the body and
without it, we would just be a trillions cells without a
shape or function. It is essentially the mortar between
the bricks. The skin, bones, cartilage, tendons and
ligaments are examples where the ECM is located in the
body. The ECM is composed of material (fibrous elements)
called elastin and collagen surrounded by a gelatinous
substance (Hyaluronic Acid). HA's roles in the ECM is to
help the stretchy fibers in the body from overstretching
and drying out by continually bathing them in this
nutritious water base gelatinous fluid. It also serves
as a wonderful medium through which nutrients and waste
are transported to and from the cells of these
structures. This fluid would not exist if it was not for
the ability of the HA molecule to bind up to 1000 times
its weight in water.
Hyaluronic Acid in
the skin
The skin is the
largest organ in the body comprising about 15% of the
body weight. Roughly 50% of the Hyaluronic Acid in our
body is found in the skin. HA and Collagen are vital to
maintaining the skin’s layers and structure. It is the
collagen that gives the skin its firmness but it is the
HA that nourishes and hydrates the collagen. Imagine the
collagen as the stretchy fibers that restore the skin
back to shape when stretched. Collagen is like a rubber
band but stretch that rubber band a million times, like
what we do with our skin and without any moisture.
Eventually that rubber band gets overstretched (saggy)
and dried out and will most likely break. This is much
the same way the collagen in our skin reacts leaving our
skin in need of moisture. Now imagine that same rubber
band stretched a million times while under water the
whole time. Chances of that rubber band drying out and
breaking are minimal. Consider the Hyaluronic Acid as
the water that keeps the collagen moist and elastic.
Collagen is continuously surrounded and nourished by the
gelatinous HA substance. Young skin is smooth and highly
elastic because it contains high concentrations of
Hyaluronic Acid, which helps skin stay healthy. As we
grow older, the body loses its ability to maintain this
same concentration in the skin. With decreasing levels
of HA in the skin, so goes the ability of the skin to
hold water. The result, the skin becomes drier and loses
its ability to maintain it's hydration. Hyaluronic acid
acts as a space filler by binding to water and thus
keeping the skin wrinkle-free.
Episilk™ Shampoo
An
all natural Hyaluronic Acid shampoo that helps to
revive dry, lifeless hair by restoring the HA that
time takes away. Episilk™ Shampoo with HA helps to
maintain proper scalp condition healthy, lustrous
hair. A healthy, nourished scalp can help provide
Code: HYL02
Price: $14.95
Promote
healthy hair and scalp with this unique hyaluronic
acid shampoo. Episilk™ shampoo is suitable for all
hair types including permed or color-treated. This
shampoo's excellent moisturizing action helps relieve
dry conditions of the scalp and leaves hair feeling
soft and manageable.
Key Features:
- All-natural, no harmful parabens, spa
tested and fragrance free
- Infused with premium, high molecular
weight hyaluronic acid
- Gentle, moisturizing formula
- High quality shampoo that lightly
cleanses while it moisturizes; leaving hair and the
scalp soft and health
Is Episilk™
shampoo natural?
Yes it is. Hyaluronic acid, aloe vera, chamomile, and
peppermint oil are all natural ingredients.
Can I use Episilk™ shampoo with my other hair care
products?
Yes. Episilk™ shampoo can be used with any other hair
products and works especially well when used prior to
using Episilk™ light-weight conditioner.
What can hyaluronic acid do for my hair and scalp?
Structurally the scalp is identical to the skin tissue
located throughout the body except it also contains
about 100,000 hair follicles that give rise to hair.
Actually the hair and the hair follicle are a derivative
of skin tissue. There are two distinctive skin layers,
one, the epidermis (outer layer) which gives rise to the
protective shield of the body and the other, the dermal
layer (deep layer) which makes up the bulk of the skin
and is where the hair follicle is located. This dermal
layer is composed of connective tissue and the
connective tissue, with its gelatinous fluid like
characteristics provides support, nourishes and hydrates
the deep layers of the scalp. The result is healthy
lustrous hair and a moisturized scalp. Again, all of
this is made possible because of the presence of HA in
the scalp tissue and its ability to form this fluid and
hold water.
Episilk FRS Serum
Code:
HYL03 Price: $39.95
Our
super moisturizing Hyaluronic Acid serum combined with
the wrinkle reducing hexapeptide, Argireline®. We
call it FRS- Facial Relax Serum. See for yourself what
this miracle combination can do for you! 30 ml (1oz.)
bottle
Episilk™ FRS Serum is
a powerful combination of Hyaluronic Acid and
Argireline® designed to hydrate, nourish and relax
expression lines to lessen the appearance of wrinkles.
Key
Features:
- Natural, no harmful parabens, spa tested and
fragrance free
- Premium, high molecular weight hyaluronic
acid
- Contains Argireline® to help relax
expression lines
- High quality formula lessens the appearance
of wrinkles, while moisturizing the skin
What is
Argireline?
Argireline® is a unique hexapeptinde that has been
shown to relax and smooth expression lines around the
eyes, forehead and mouth to lessen the appearance of
wrinkles.
How does
Argireline reduce wrinkles?
Argireline® relaxes facial tension, leading to the
relaxation of facial muscles that contribute to lines
and wrinkles. Clinical research shows that Argireline
works by inhibiting the release of neurotransmitters
released by the brain that tell these facial muscles to
tense. The result is relaxed musculature and reduced
wrinkles and lines.
Directions for
use:
Apply morning and night to clean skin. Use a small
amount, gently messaging into desired areas. For best
results, use after Episilk PHA Serum. For external use
only. Do not use if seal is broken.
Ingrediants
water, Argireline® (acetyl hexapeptide-8),
vegetable glycerin, sodium hyaluronate (hyaluronic
acid), xanthan gum, aloe vera juice, lactoperoxidase,
glucose oxidase, glucose, wheat extract, asian
ginseng, echinacea.
Episilk
IFL Serum
Code: HYL04
Price: $39.95
Episilk™ IFL
(Instant Facelift Serum) serum is a unique, natural
serum which contains a combination of Hyaluronic Acid
for moisturizing and Pepha®-Tight for tightening
and smoothing fine wrinkles.
Episilk™ IFL
Serum is an effective combination of Hyaluronic Acid
and Pepha®-Tight designed to hydrate and support
the natural firmness and elasticity of the skin.
Soothe, nourish and rejuvenate your skin while
reducing the appearance of wrinkles.
Hyaluronic
Acid(HA) is an important element of skin known for its
ability to bind up to 1000 times its weight in water.
The body’s HA production naturally decreases with age,
leaving the skin dry and wrinkled. Replenishing the
body’s natural HA allows skin to retain moisture and
provides volume, form and lift.
Pepha®-Tight
is a unique ingredient with the ability to support the
skin’s natural firmness and vitality. It is derived
from a microalgae and designed to firm and tighten
skin while at the same time promoting a healthy
collagen network.
What causes
wrinkles and when do they start?
A variety of factors can cause wrinkles. Free radicals,
ultraviolet and visible light, and pollutants, like smog
and cigarette smoke, all shrink and thin the cells that
give the skin shape and hold it firm. The effects of
damaging factors are cumulative. Over time skin loses
its ability to hold its shape and firmness. The result
is wrinkles. Skin, movement and gravity only add to the
problem. There is no specific age when wrinkles start;
it can depend on heredity and lifestyles. Unfortunately,
at some point in time everyone gets them.
Can I use
IFL serum with your other serums, like the FRS?
Yes, you can use the IFL in conjunction with any of our
other products. Many people find that the IFL works best
on wrinkles around the eyes and mouth, and they find the
FRS works best with wrinkles on the forehead and brows
How long
will it take to see results and how long do they
last?
Pepha®-Tight tightens the skin immediately and has a
long term beneficial effect. Results may last for
months, even if use of the formula is ended.
Nonetheless, Episilk™ IFL serum will continue to restore
and revive your skin as long as you use the product.
Can I use
this with my other skin care products?
Yes. Episilk™ IFL serum can be used with any skin care
products.
What is
Pepha™-Tight?
Pepha™-Tight is a unique ingredient with the ability to
support the skin’s natural firmness and vitality. Using
highly purified biotechnologically process produced
extract from the micro algae, Nannochloropsis oculata. A
special fermentation technology and optimal growth
conditions ensure the high quality and pureness of the
algae extract.
What are the
ingrediants?
water,
Pepha®-Tight (pullulan, algae extract), sodium
hyaluronate (hyaluronic acid), zinc glyconate, xanthan
gum, vegetable glycerin, vitamin A, citric acid,
glucose, lactoperoxidase, glucose oxidase
Episilk
PHA Serum
Code:
HYA05 Price: $59.95
A premium HA serum
that is designed for maximum moisturizing and softening.
Hyaluronic Acid(HA) is
an important element of skin known for its ability to
bind up to 1000 times its weight in water. The body’s HA
production naturally decreases with age, leaving the
skin dry and wrinkled. Replenishing the body’s natural
HA allows skin to retain moisture and provides volume,
form and lift.
Episilk™ PHA Serum is
an intensely hydrating serum that rejuvenates skin from
the inside out. It improves the tone and appearance of
skin by enhancing the skin’s ability to retain moisture.
Its light, non-oily texture soothes skin leaving it
fresh and soft while smoothing fine lines and wrinkles.
PHA Serum renews your skin’s suppleness and elasticity.
Nourish and
Moisturize Your Skin with HA
50% of the HA found in
the body is found in the skin layers of the dermis and
epidermis. HA keeps skin hydrated and provides
nourishment. With age, the ability of the skin to
produce HA decreases leaving the skin unhealthy and
wrinkled. HA has been shown when topically applied,
keeps skin hydrated and wrinkle-free. HA is the subject
of a great deal of research because of it’s amazing
properties to rejuvenate and moisturize the skin.
What is Episilk™
PHA(Pure hyaluronic acid) Serum?
Episilk Serum is a
100% natural HA facial serum that contains high
concentrations of premium grade hyaluronic acid.
Episilk™ PHA Serum contains no synthetic preservatives
or other ingredients known to cause skin irritations.
Packaged in a 1oz. (30ml) bottle. Ingredients are
hyaluronic acid and sterile water.
Why is
hyaluronic acid so important to the skin?
Young skin is smooth
and highly elastic because it contains high
concentrations of hyaluronic acid, which helps skin stay
healthy. As we grow older, the body loses its ability to
maintain this same concentration in the skin. As a
result, the skin becomes dry and wrinkled.
How long has
hyaluronic acid been used?
Hyaluronic acid was
first used commercially in 1942 when Endre Balazs
applied for a patent to use it as a substitute for egg
white in bakery products. He went on to become the
leading expert on HA, and made the majority of
discoveries concerning HA. Hyaluronic acid has long been
used in some of the top selling commercial skincare
products, however, due to its high cost, it was only
used in small concentrations.
Because it is an
acid will it burn my skin?
Hyaluronic acid is
often called an acid and this is a misnomer. Hyaluronic
acid as a sodium salt (sodium hyaluronate)(Episilk™)
will have a neutral pH measurement not an acidic.
Because of the water retention capacity of hyaluronic
acid, it is actually very good for skin health.
Are there any
clinical studies that have been done with hyaluronic
acid?
Yes, hyaluronic acid
has been one of the most heavily researched subjects
over the past 20 years with many clinical studies in the
field of dermatology and cosmetic surgery.
What are the
directions for use with Episilk PHA Serum™?
Apply twice a day
after washing. Use a small amount to the side or back of
the hand and mix with just a drop of water. Since our
serums are concentrated be a better value, adding a drop
of water may help to activate the ingredients.
What are
the Ingrediants?
De-ionized water, sodium hyaluronate (hyaluronic acid)
Dr. John's
Tooth Gel
Code: HYA06 Price $9.95
A great tasting,
fluoride-free toothpaste that supports healthy gums
and teeth and promotes good dental health.
Dr. John’s Formula toothpaste gel is a fluoride-free
toothpaste gel that uses pure hyaluronic acid and
xylitol, with hint of mint to promote dental health and
support healthy gums and teeth.
KEY FEATURES
- All natural, great tasting toothpaste gel
- Free of sodium lauryl sulfate, flouride, and
artificial colorings and flavors
- Enriched with hyaluronic acid
- Sweetened naturally with xylitol and
peppermint oil
How does
hyaluronic acid aid in gum health?
The gums are composed of dense fibrous connective tissue
which secure the teeth to the aveloar bone. This
connective tissue is composed of a fibrous tissue
surrounded by hyaluronic acid. If the HA is present, it
helps to provide the tensile strength of the ligaments
that secure the tooth in place by providing hydration
and nourishment.
What is
xylitol?
Xylitol is a sugar alcohol sweetener that is commonly
used a naturally occurring sugar substitute. Some of the
most popular sources of xylitol come from berries, corn
husks, oats, and mushrooms. Studies have shown xylitol
to support healthy plaque levels on teeth and gums, thus
making it a common ingredient for natural dental health
care products.
Is Dr. John’s
Formula natural?
Yes, it is. Hyaluronic acid and xylitol are all natural
ingredients.
Can Dr. John’s
Formula be used with other dental products?
Yes, it can. Dr. John’s Formula can be regularly used
with other dental products. Customers have not changed
their previous dental regimens.
What are the
Ingrediants?
SODIUM HYALURONATE (HYALURONIC ACID), SORBITOL, WATER,
HYDRATED SILICA, XYLITOL, GLYCERIN, ZINC CITRATE
TRIHYDRATE, SODIUM LAUROYL SARCOSINATE, PEPPERMINT OIL,
XANTHUM GUM
